Semaglutide (GLP-1)
Characteristics
- Chemical Name: Semaglutide
- Other Name(s): GLP-1 receptor agonist; NN9535
- CAS: 910463-68-2 (reported)
- Powder Purity: ≥ 98% (HPLC)
- Solubility: Soluble in water and buffered aqueous solutions; stability and solubility influenced by pH and ionic conditions
- Molar Mass: ~ 4,113.6 g/mol (reported range)
- Chemical Formula: C₁₈₇H₂₉₁N₄₅O₅₉
- Shelf Life: Up to 24 months when stored lyophilized at −20 °C or below, protected from light and moisture
- Appearance: White to off-white lyophilized powder
- Biological Half-Life: Approximately 7 days (extended via fatty diacid side-chain enabling albumin binding)
- Safety Compliance:
- Not approved for human or animal consumption
- Not intended for diagnostic, therapeutic, or clinical use
- Handle by trained professionals using appropriate laboratory safety procedures
Description
Semaglutide is a synthetic peptide research compound that functions as a selective agonist of the glucagon-like peptide-1 (GLP-1) receptor, a key pathway involved in glucose regulation, appetite signaling, and metabolic homeostasis. Structurally modified with a fatty acid side chain, it exhibits prolonged activity through albumin binding, making it of interest in studies involving incretin biology, receptor signaling, and metabolic regulation.
Semaglutide is widely studied in the context of appetite control, insulin secretion, and gastric emptying dynamics. It is typically supplied as a lyophilized powder for laboratory and analytical applications. This compound is not intended for human or animal consumption and is provided strictly for scientific research purposes.






