Retatrutide (GLP-3)
Characteristics
- Chemical Name: Retatrutide
- Other Name(s): LY3437943; Triple incretin receptor agonist (GLP-1 / GIP / Glucagon), GLP-3
- CAS: 2381089-83-2 (reported)
- Powder Purity: ≥ 98% (HPLC)
- Solubility: Soluble in water, PBS, and dilute acidic buffers (e.g., acetic acid); solubility dependent on pH and concentration
- Molar Mass: ~ 4,770–4,800 g/mol (reported range)
- Chemical Formula: C₂₂₁H₃₄₂N₄₆O₆₆ (reported)
- Shelf Life: Up to 24 months when stored lyophilized at −20 °C or below, protected from light and moisture
- Appearance: White to off-white lyophilized powder
- Biological Half-Life: Approximately 6 days (prolonged via fatty-acid side-chain modification; research reference value)
- Safety Compliance:
- Not approved for human or animal consumption
- Not intended for diagnostic, therapeutic, or clinical use
- Handle by trained professionals using appropriate laboratory safety procedures
Description
Retatrutide is a synthetic peptide research chemical that functions as a triple agonist of the GLP-1, GIP, and glucagon receptors, key signaling pathways involved in metabolic regulation and energy balance. It is designed to simultaneously engage multiple incretin and glucagon pathways, making it of interest in advanced metabolic and receptor-pharmacology research. Retatrutide is typically supplied as a lyophilized powder for laboratory and analytical use only. This compound is not intended for human or animal consumption and is offered strictly for scientific research purposes.










